Electroanalytical Methods Group

The research of the electroanalytical group is focused on the development of electrochemical sensors and sensor-based analytical methods. The development of new sensors for the pharmaceutical industry and biomedical applications represents an important challenge in contemporary analytical chemistry. In contrast to separation and spectrometric techniques, electrochemical sensors, in addition to the required selectivity and sensitivity, offer low-cost and time-efficient methods suitable for large-scale screening.

Beyond these advantages, their use in biomedical applications is also supported by their high sensitivity and selectivity. The selectivity of a sensor is closely related to the design of its receptor. The synthetic part of the “Molecular Recognition” group led by Prof. V. Král prepares receptors bearing functional groups that detect biologically relevant analytes, a key component of screening tests for various diseases.

Head:

doc. Mgr. Taťjana V. ŠIŠKANOVA, CSc.

Members:

Ing. Gabriela Broncová, Ph.D.

PhD Students:

Ing. Eva Pospíšilová (TŠ)

Ing. Kristýna Havelková (GB)

Ing. Sára Festová(GB)

supervisors: TŠ = doc. Šiškanova, GB = dr. Broncová

 

 

Miniaturized electrochemical sensors can provide crucial information regarding health and safety in real time. Moreover, commercial electrochemical sensors for the determination of glucose and lactate improve the quality of life for diabetics and athletes.

Main research topics of the electrochemical group:

  • Chemically and electrochemically modified electrode surfaces
  • Nontraditional electrode materials
  • Nanoparticles for electrochemical detection
  • A miniaturization of electrodes: noninvasive monitoring of biologically significant analytes
  • Propagation of electrochemical methods among students

Cooperations:

Prof. Vladimir M. Mirsky

Brandenburg University of Technology Cottbus – Senftenberg, Germany

Prof. Martin Vrňata

University of Chemistry and Technology Prague, Department of Physics and Measurements

Prof. Pavel Matějka

University of Chemistry and Technology Prague, Department of Physical Chemistry

Dr. Martin Kuchař

University of Chemistry and Technology Prague, Laboratory of Forensic Analysis of Biologically Active Substances

Prof. RNDr. Jiří Barek

Charles University, Department of Analytical Chemistry

 

Selected scientific papers:

Shishkanova T.V., Broncová G., Fitl P., Král V., Barek J.: Voltametric detection of catecholamine metabolites using Tröger base modified electrode, Electroanalysis 30 (2018), 734-739. DOI: 10.1002/elan.201700635 https://doi.org/10.1002/elan.201700635

Broncová G., Matějka P., Němečková Z., Vrkoslav V., Shishkanova T.V.: Electrochemical detection of sialic acid using phenylboronic acid-modified poly(diaminobenzoic) acid, Electroanalysis 30 (2018), 672-680. DOI: 10.1002/elan.201700634 https://doi.org/10.1002/elan.201700634

Shishkanova T.V., Havlík M., Král V., Kopecký D., Matějka P., Dendisová M., Mirsky V.M.: Amino-substituted Tröger’s base: electrochemical polymerization and characterization of the polymer film, Electrochim. Acta 224 (2017), 439-445. https://doi.org/10.1016/j.electacta.2016.12.061

Shishkanova T.V., Fitl P., Král V., Barek J.: Nanoparticles functionalized with phenylboronic acid for the potentiometric detection of saccharides, J. Electroanal. Chem. 761 (2016), 106-111. https://doi.org/10.1016/j.jelechem.2015.12.009

Shishkanova T.V., Havlík M., Dendisová M., Matějka P., Král V.,: Synthesis and deposition of a Troger's base polymer on the electrode surface for potentiometric detection of a neuroblastoma tumor marker metabolite, Chem. Commun. 52 (2016), 11991-11994. DOI: 10.1039/c6cc06203b http://pubs.rsc.org/en/content/articlepdf/2016/cc/c6cc06203b