Separation Methods and Biomedical Chemistry Group
At the Department of Analytical Chemistry, the Separation Methods and Biomedical Chemistry Group focuses on two main areas of scientific research.
The first area is the development of modern separation techniques in liquid and gas chromatography, including mass spectrometry and capillary electrophoresis. Various topics are addressed, in particular the development of new methods for the separation of a broad range of analytes with an emphasis on pharmaceuticals and illicit drugs, as well as the monitoring of pharmacokinetics of selected analytes in living organisms. An important part of the work is also active participation in the development of new potential drugs.
The second area of research involves the application of analytical chemistry methods for the preparation, separation, and study of biomedical systems based on biologically active compounds, including small synthetic molecules and natural products. The group addresses a wide range of topics, in particular the design of molecular systems for analyte detection, the study of interactions of bioactive compounds, the design of molecular sensors and probes, the development of formulations and delivery systems, and the analysis of pharmaceutical substances.
| Head: |
prof. Dr. RNDr. David SÝKORA |
| Members: |
RNDr. Pavel Zachař, CSc. |
| PhD Students: |
Ing. Jana Fialová (DS) - přerušeno Ing. Magdalena Vágnerová (DS) Ing. Aneta Čechová (DS) |
|
supervisors DS = prof. Sýkora |
Equipment:
The group is equipped with adequate instrumentation, including GC-MS/MS, LC-MS/MS, and MALDI-TOF/TOF.
R&D and cooperation:
The group participates in many Czech and international research projects and cooperates with the application sphere. Within the framework of several projects, it is closely connected to many prestigious institutions, including BIOCEV, the First Faculty of Medicine of Charles University, and FHNW in Basel.