Separation Science, Medicinal and Forensic Chemistry Group

The Group of Separation Science, Medicinal and Forensic Chemistry at the Department of Analytical Chemistry focuses its research on two main areas.

The first area is the development of advanced liquid chromatography–based separation techniques, particularly in combination with mass spectrometry, for the analysis of potential new pharmaceuticals and drug candidates.

The second area focuses on developing novel separation methods for a broad range of analytes, with particular emphasis on illicit drugs and counterfeit pharmaceuticals. In parallel, the group develops innovative forensic techniques for both group and individual human identification, as well as other applications in forensic science.

Head:

prof. Dr. RNDr. David SÝKORA

Members:

RNDr. Pavel Zachař, CSc.

prof. Ing. Milan Jakubek, Ph.D.

PhD Students:

Ing. Marek Šimko (DS)

supervisors  DS = prof. Sýkora

 

Equipment:

The research group is equipped with state-of-the-art analytical instrumentation, including GC–MS/MS, LC–MS/MS, and MALDI-TOF/TOF systems.

Research and Collaborations:

The group regularly secures competitive research funding and collaborates closely with both academic institutions and industrial partners. Through several research projects, it maintains active collaborations with leading research organizations, including the Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences (IOCB Prague), BIOCEV, the First Faculty of Medicine of Charles University, and numerous international partners.

Research projects involve students at the bachelor's, master's, and, most prominently, doctoral levels. The group's scientific findings are regularly published in high-impact international peer-reviewed journals.