The group focuses on the development of advanced methods of vibrational spectroscopy and microspectroscopy, with an emphasis on overcoming the current limitations of vibrational spectroscopic techniques (such as lowering detection limits, achieving nanoscale resolution, improving system stability, etc.).
We primarily focus on surface-enhanced techniques, namely surface-enhanced Raman scattering (SERS) and surface-enhanced infrared absorption (SEIRA). These methods exploit the enhancement of analyte spectral signals resulting from interactions with electromagnetic radiation on nano- and micro-structured plasmonic substrates (based on noble metals).
Currently, the group’s research is oriented mainly toward the use of both conventional and surface-enhanced spectroscopic techniques for trace detection and identification of pharmaceuticals, natural compounds (especially secondary plant metabolites), addictive alkaloids, and corrosion products on metal surfaces. Various real and model systems are studied to elucidate the barrier and permeation properties of cellular membranes, skin components, and entire layers that influence the bioavailability of topical and transdermal drug formulations.
